Job Description Summary
LI#-Onsite (Lab Based)
Internal Title: Senior Scientist II
Location: Cambridge
This role is based in Cambridge, MA. Novartis is unable to offer
relocation support for this role: please only apply if this location is accessible for you.
As a Senior Scientist II in our Translational Medicine Drug Disposition Discovery Bioanalytical group, you will join a dynamic and high-performing team at the Cambridge site. You will provide timely methods and high-quality data reports for drug discovery projects and liaise with partners to ensure smooth workflows and effective communication. We offer a collaborative culture, opportunities for growth, and competitive salaries and benefits.
The successful candidate will join a dynamic, innovative and high performing global discovery bioanalysis team and play a key role as a senior lab scientist for the Cambridge bioanalysis lab.
Job Description
Key responsibilities:
- Provide internal lab based bioanalytical support investigating the PK/TK properties of low molecular weight and novel modality compounds.
- Responsible for setting up the new LC-MS workflow by engaging with the key stakeholders.
- Provide mentorship and insights for junior associates to support advance method development for custom discovery PK and PKPD.
- Collaborate as a subject matter expert in bioanalysis with biotransformation, in vitro and in vivo colleagues, as well as chemists and biologists with project teams.
- Independently conceives and runs complex experiments/workflows that implement project strategy.
- Analyzes, writes reports and communicates own results in the project meetings.
- Implement technologies such as LC-MS/MS, SFC-MS/MS or LC-HRMS for low molecular weight and novel modality compounds.
- Explore automation and software related solutions to increase workflow efficiency.
- Collaborate with our CRO partners for special case custom BA method transfers to the CRO.
- Utilizes established networks and builds new network connections, including outside of own department.
- Comply with local and Novartis-specific rules and regulations.
Essential requirements:
- B.S. (6+ years) or M.S. (4+ years) or PhD degree (1+ years) of bioanalytical lab scientist in biotech or pharma industry.
- Agility to independently perform high quality and fit-for-purpose bioanalysis within short timelines. Emerging scientific leader with good values and behaviors.
- Hands on experience in custom method development, variety of sample preparation (SPE, LLE, IMC etc.) and quantitative analytical methods for LC-MS (low- and high-resolution) are required.
- Agility to adapt and shift priorities as per business needs.
- Practices efficient time management to work under tight timelines, focuses on deliverables, and effectively prioritize when designing/undertaking experimental plan.
- High motivation, curiosity and creativity and the ability to thrive in a matrixed work environment and communicate effectively within multidisciplinary teams.
- Good oral and written communication and presentation skills to communicate key results to internal teams.
Desirable Requirements:
- Experience with BA data analysis and reporting PK/TK data is highly preferred.
- Proven track record of establishing new lab workflows is preferred.
