Senior Research Associate, Immunobiology

We are seeking a creative and technically strong immunology-focused discovery scientist to join our Immunobiology team. The ideal candidate will have expertise in T cell engager biologic functional assessment, including tumor killing, cytokine production, T cell exhaustion assays, and multiparameter flow cytometry immune cell analysis. Experience in T cell engager discovery, particularly in evaluating CD3 bispecifics or costimulatory biologics, is preferred. The successful candidate will contribute to the discovery and assessment of novel costimulatory T cell engagers to determine key differentiation design features and supporting mechanisms of action. This includes designing and performing functional assays to prioritize alternative protein designs based on tumor killing potency, cytokine release and immune modulation mechanism of action. Collaboratively design in vivo proof of principle studies to test in vitro-driven hypothesis on molecule prioritization, mechanism of action, lead assessment, and selection of preclinical models to evaluate immune pharmacodynamic and establish in vivo mechanisms of differentiation. They will also work closely with our biotherapeutics and in vivo pharmacology research teams to drive T cell engager platform discoveries to drug development programs. Strong verbal and written communication skills are necessary, as is a proven track record of scientific and project achievements in biopharma. We are looking for a candidate who thrives in a collaborative, team-oriented environment and is eager to leverage the growth opportunities within a matrixed organization. This is an exceptional opportunity for a scientist passionate about T cell engager platform discovery and driven to translate innovative research into novel therapeutics.