Senior Engineer, Small Molecule Process Development and Manufacturing

About This Role:

We are seeking a highly motivated and creative Chemical Engineer to join our Small Molecule Chemical Development team. This position provides an exciting opportunity to develop robust processes for the synthesis of a wide range of assets across various modalities. As a Senior Engineer, you will gain experience in early to late-phase drug development and exposure to designing and developing manufacturing processes for clinical and commercial therapeutics. You will collaborate with a team of organic chemists and chemical engineers in designing innovative processes that supply new medicines to patients.

Who We Are:

We are a team of organic chemists and chemical engineers engaged in the design of innovative processes which supply new medicines to patients. We focus on developing safe, economical, sustainable, cost-effective, and robust processes to support clinical trials and the launch of new medicines across various drug modalities. We are driven by first principles science, data-driven decision-making, and collaborative teamwork.

What You’ll Do:

• Collaborate with development and manufacturing teams to design and conduct laboratory experiments aimed at optimizing and characterizing processes.
• Design and execute experiments to advance the portfolio, analyzing and sharing data to implement efficient and robust chemical processes.
• Manage key laboratory instrumentation
• Develop fundamental process knowledge for transitioning processes from lab scale to manufacturing partners.
• Collaborate with Process Chemistry, Analytical Chemistry, Solid Form, and Separations colleagues to support clinical material supply and regulatory filings.
• Write research reports, present data in team meetings, and engage in CMC activities, including authoring CMC sections of INDs.
• Interact with Contract Research Organizations as project needs evolve.
• Initiate innovative research projects to improve process understanding and control.
• Mentor and guide earlier career team members.

Who You Are:

You have a passion for exploring novel scientific concepts and are eager to contribute to the design, development, and execution of cutting-edge technologies in the service of delivering drug candidates for clinical trials. Your vision and dedication drive you to push the boundaries of scientific endeavors, ultimately impacting patient lives. You thrive in a collaborative environment where urgency, accountability, inclusion, and integrity are shared values.

Required Skills:

• Ph.D. with 5+ years of relevant experience.
• M.S. with 6+ years of relevant experience in pharmaceutical or biotech settings.
• BS with 7+ years of relevant experience in pharmaceutical or biotech settings.
• Strong background in pharmaceutical chemical engineering, including crystallization techniques, process characterization, process safety, and tech transfer protocols.
• Experience in crystallization of APIs and familiarity with analytical tools and purification techniques.
• Ability to work both independently and collaboratively.
• Good communication skills and the desire to work in a collaborative team environment.

Preferred Skills:

• Experience with process characterization, crystallization techniques, drug substance form control, and familiarity with process safety protocols.
• Demonstrated problem-solving skills in pharmaceutical chemical engineering.

Job Level: Management