Senior Director, Medical Strategy and Operations

Overview

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.

This role will serve as a strategic and operational partner to the Vice President of Medical Affairs and Medical leadership team, and is responsible for ensuring that medical capabilities, processes, systems, and execution models are efficient, compliant, scalable, and aligned with Alumis’ growth strategy. The Senior Director, Medical Strategy and Operations, will be responsible for advancing key initiatives aimed at optimizing and showcasing the impact of the Medical Affairs team. This is a hands-on position that includes driving medical strategic initiatives, enhancing the Medical Affairs systems, supporting critical medical insights processes, and developing innovative solutions to measure and report on medical affairs performance and impact. The role demands an individual who combines scientific knowledge with strong operational leadership to thrive in a fast-paced, agile environment to elevate our medical affairs capabilities.

Key Responsibilities:

Strategic Leadership:

• Lead and drive the development and execution of initiatives that elevate the strategic and operational effectiveness of the Medical Affairs team in a consistent and scalable manner.

Medical Affairs Systems Optimization:

• Oversee the design, implementation, and optimization of our Medical Affairs systems to improve internal efficiencies, engagement and communications with key opinion leaders (KOLs), healthcare providers, and other relevant stakeholders.
• Lead continuous improvement initiatives to enhance efficiency, quality, and compliance across the Medical function.
• Implement best practices for operational metrics, KPIs, dashboards, and reporting to support data-driven decision-making.

Medical Insights:

• Collaborate with Medical Affairs Leadership to collect, analyze, and integrate valuable medical insights that inform strategic decisions and optimize the impact of our medical programs.

Content Management:

• Serve as Medical Affairs content owner through review and approval process for external-facing materials.

Cross-functional Collaboration

• Collaborate with other functional areas such as Clinical Development, Marketing, Market Access, Commercial, Analytics, Compliance, and Regulatory to ensure alignment and integration of medical excellence within the broader organizational strategy.

Guidance and SOP Development:

• Leverage expertise to develop guidance documents and SOPs to foster consistency, clarity, and accountability across Medical Affairs.

Planning, Budgeting & Resource Management

• Lead medical annual planning, forecasting, and budget management.
• Optimize headcount planning, vendor strategy, and external spend to maximize impact and efficiency.
• Provide transparency and insights into medical investments and their impact.

Qualifications:

Experience:

Minimum of 10 years in Medical Affairs leadership. Proven experience in managing and optimizing medical operations, systems, content, and medical insights. Experience in a fast-paced, small biotech environment a plus

Education:

Advanced degree (PhD, MD, MBA, PharmD or similar)

Leadership Skills:

Exceptional leadership abilities with a demonstrated ability to manage cross-functional teams and drive change across complex medical operations. Must have track record of effectively leading without authority

Operational Expertise:

Strong experience in developing and managing Medical Affairs dashboards and other qualitative outcomes to measure impact and performance.

Strategic Thinking:

Ability to develop and implement strategic initiatives aligned cross-functionally that drive organizational goals and enhance the impact of Medical Affairs functions.

Strong Communication:

Excellent communication and interpersonal skills, with the ability to engage and influence stakeholders at all levels, both internally and externally.