Senior Director, Clinical Value & CAR-T Market Expansion, US Medical Affairs

Head, Senior Director US Medical Director Clinical Value & Market Expansion (CAR‑T)

Role Purpose

The Head, US Clinical Value & Market Expansion (CAR‑T) is responsible for defining and executing the US Medical Affairs market expansion & US community oncology strategy to expand appropriate patient access to CAR‑T therapies across academic and community settings. This role owns the US clinical value narrative, evidence strategy, and medical field execution (in coordination with global teams) required to activate referral pathways, support site readiness, and enable confident adoption of CAR‑T in real‑world practice.

The role provides direct leadership to the US Clinical Value Liaisons (CVLs) and the Associate Director, US Medical Strategy – CAR‑T Market Expansion, ensuring alignment between strategy, evidence generation, and field execution.

This position will be field based.

Key Responsibilities

Clinical Value & Evidence Strategy

• Define and own the US clinical value framework for CAR‑T, translating clinical data into clear, credible narratives for diverse stakeholders.
• Lead US Medical Affairs input into evidence generation priorities, including real‑world evidence, outcomes research, site‑level insights, and unmet need characterization.
• Ensure consistent, compliant scientific messaging across the CVL team and broader Medical Affairs organization.

Market Expansion & Community Oncology Enablement

• Develop and execute the US Medical market expansion strategy for CAR‑T, with emphasis on:
• Community oncology engagement and referral pathway activation
• Site onboarding, readiness, and safe sequencing education
• Removal of clinical and operational misconceptions limiting adoption
• Partner with internal stakeholders to ensure medical strategies effectively support appropriate patient identification and timely referral.

Field Medical Leadership (CVLs)

• Provide direct people leadership, coaching, and performance management for the Clinical Value Liaison (CVL) team.
• Set priority accounts, engagement models, and field medical objectives aligned to US market expansion goals.
• Ensure CVLs deliver high‑impact scientific exchange focused on clinical decision‑making, outcomes, and real‑world application
• Coordinating and collaborating with HEOR / RWE team in global
• Coordinate and collaborate with commercial Market Access team

Strategic Integration & Cross‑Functional Partnership

• Serve as the primary US Medical Affairs interface for CAR‑T market expansion with:
• Market Access Commercial team (without promotional overlap)
• Global Strategy team
• Collaborate on how materials for MSL & CVL team are created
• Global Medical Affairs Evidence Generation (HEOR / RWE) and Clinical Development teams
• Ensure clear role delineation and strong alignment across functions to accelerate execution while maintaining medical integrity.

Leadership & Governance

• Represent US Medical Affairs in leadership forums related to CAR‑T expansion, evidence strategy, and field execution.
• Contribute to budget planning, headcount strategy, and prioritization decisions impacting US Medical Affairs outcomes.

Direct Reports

• Clinical Value Liaisons (CVLs), US
• Associate Director, US Medical Strategy – CAR‑T Market Expansion

Qualifications & Experience

• MD, PharmD, PhD, or equivalent advanced scientific or clinical degree.
• 14 years+ experience with BS/BA or 12 years+ experience with MS/ MA or MBA
• Significant experience in US Medical Affairs within oncology or hematologic malignancies; CAR‑T experience strongly preferred.
• Deep understanding of community oncology dynamics, referral pathways, and real‑world treatment barriers.
• Experience with US payer, large community oncology networks and how community practices operate in the US healthcare system (including community motivations, etc)
• Demonstrated success leading field medical teams and translating clinical data into practice‑changing medical strategy.
• Strong communication skills / presenting to both internal and external audiences
• Proven ability to operate at the intersection of strategy, evidence, and execution in a complex matrixed environment.

People Leader Accountabilities:

• Create Inclusion - knowing the business value of diverse teams, modeling inclusion, and embedding the value of diversity in the way they manage their teams.
• Develop Talent - understand the skills, experience, aspirations and potential of their employees and coach them on current performance and future potential. They ensure employees are receiving the feedback and insight needed to grow, develop and realize their purpose.
• Empower Teams - connect the team to the organization by aligning goals, purpose, and organizational objectives, and holding them to account. They provide the support needed to remove barriers and connect their team to the broader ecosystem.