Scientist – Preclinical Team

About Capricor Therapeutics

Capricor Therapeutics (NASDAQ: CAPR) is a biotechnology company dedicated to advancing transformative cell and exosome-based therapies for rare diseases. At the forefront of our innovation is Deramiocel(_CAP-1002_), our lead cell therapy in late-stage development for Duchenne muscular dystrophy. We are also harnessing our proprietary StealthX™ exosome platform to unlock new possibilities in targeted delivery and vaccinology. Every program reflects our commitment to pushing the boundaries of science and delivering life-changing treatments to patients and families who need them most.

We are seeking a Science to join our Pre-Clinical team to support the progression of our therapeutic programs through the design, execution, and optimization of in vivo research activities and preclinical studies. This role requires deep expertise in in vivo methodologies, strong technical skills, and the ability to perform complex operations in a regulated environment.

Responsibilities

• Partner with the Principal Scientist and Director to provide preclinical expertise, including animal handling and study design.
• Plan, execute, and analyze in vivo and ex vivo studies to support program objectives.
• Perform cell-based assays and tissue analyses from in vivo studies; compile and report results.
• Conduct survival surgeries and establish rodent models using aseptic techniques.
• Develop, characterize, and implement new animal models to enhance pharmacology study effectiveness.
• Maintain detailed, audit-ready documentation of all studies to ensure data integrity and traceability.
• Optimize and implement best practices for in vivo research, including model selection, dosing strategies, and sample/data collection techniques.
• Ensure compliance with regulatory guidelines and ethical standards for all preclinical activities.
• Evaluate and integrate new technologies and platforms to improve study efficiency and quality.
• Perform and interpret preclinical imaging studies (e.g., IVIS).
• Contribute to a team culture that promotes continuous improvement, ownership, and inclusion.

Minimum Requirements

• Ph.D. in a relevant scientific discipline with expertise in nonclinical operations within drug discovery and development.
• Hands-on experience with cell biology techniques, including RNA/DNA extraction, PCR, Western blot, ELISA, and interventional assays for small molecules and biologics.

Preferred Qualifications

• 2+ postdoc or industry experience
• Experience across diverse therapeutic modalities (small molecules, biologics, nucleic acid therapeutics, gene therapy).
• Familiarity with age-related disease models (inflammation, metabolic disorders, neurodegeneration, muscle atrophy, bone/joint deficits).
• Experience with metabolic chambers, behavioral assays, and related data analysis.

Work Environment and Physical Demands

• On-site laboratory environment with routine handling of animals and biological samples.
• Prolonged periods of standing and performing surgical or technical procedures.
• Ability to lift laboratory materials up to 20 pounds.

Compensation and Benefits

The posted salary range represents Capricor’s good-faith estimate of the salary range reasonably expected to be paid for this position at the time of hire. Final compensation will be determined based on job-related factors, including the candidate’s relevant experience, education, skills, certifications, scope of role, location, and internal equity.

This position may also be eligible for a discretionary annual performance bonus and, depending on the level of the role, long-term equity incentive awards in accordance with company policy.

Capricor Therapeutics offers a comprehensive benefits package that includes employer-sponsored medical, dental, and vision coverage; company-paid basic life and AD&D insurance; a 401(k) plan with company match; paid time off and company holidays; and paid parental leave. Additional voluntary benefits and wellness programs may also be available.

Why Capricor?

Capricor Therapeutics is advancing cell and exosome-based therapies with a focus on serious diseases where patients and families need new treatment options. Our work is grounded in scientific rigor, collaboration, and a shared commitment to moving meaningful therapies forward. Joining Capricor means being part of a mission-driven team working at the intersection of innovation, execution, and patient impact.

Come Work With Us

At Capricor, you’ll join a collaborative environment where employees are encouraged to contribute, grow, and help build the systems, science, and operations needed to support our next stage of growth. We value people who are thoughtful, accountable, hands-on, and motivated by work that can make a real difference.