Process Development Engineer

About eXoZymes

eXoZymes Inc. (NASDAQ: EXOZ) is a Monrovia, CA–based biotechnology company developing AI-enhanced enzymes - exozymes - to produce high-value nutraceutical and pharmaceutical ingredients from sustainable feedstocks. Our proprietary cell-free biocatalysis platform enables the conversion of low-cost inputs into bioactive compounds at near theoretical yields, providing a scalable and environmentally friendly alternative to conventional methods of producing or extracting chemicals.

Backed by public-market capital, private investment, and multi-million-dollar government grants, eXoZymes is expanding its platform, products, and team as we build the next generation of sustainable biomanufacturing technologies.

Position and Scope

We are seeking an experienced process engineer or process chemist with a background in process chemistry, chemical manufacturing, organic isolation chemistry or chemical engineering, to join our team. This person will support the development, scale, and transfer of processes to manufacture nutraceutical and pharmaceutical ingredients via our enzymatic cell-free platform. This role bridges R&D and GMP manufacturing by translating laboratory-scale processes into robust, scalable, and compliant cell-free enzymatic manufacturing processes. The ideal candidate will be an experienced chemical engineer and/or chemist who is familiar with reaction engineering, small-molecule isolation, process design, scale-up and technology transfer. The position is full-time and located in Monrovia, CA.

Duties and Responsibilities

Process Development & Optimization

• Collaborate with Development Team (comprised of scientist(s) and research associate(s)), pilot-scale manufacturing, and third-party contract development and manufacturing organizations to develop and optimize upstream and downstream processes including, e.g., cell-free reaction scale-up, target molecule purification, isolation and filtration.
• Aid in transitioning production processes from lab-scale to commercial manufacture for bioactive compounds (active and/or value-added ingredients used in the manufacture of nutraceuticals and pharmaceuticals).
• Perform scale-up and technology transfer from lab to pilot and manufacturing scale.
• Establish mechanistic and empirical models to translate biocatalytic reaction and product isolation processes into scalable, tech transfer-ready process descriptions and control strategies.
• Participate in process characterization and validation activities. Define process parameters and critical control points and establish process metrics to efficiently scale cell-free enzymatic reactions.
• Independently design and execute experiments (DoE) to improve yield, quality, robustness, and cost efficiency.
• Author and review process descriptions, batch records, SOPs, and technical reports for technical transfer packages.
• Work closely with Analytical Development, Quality and Regulatory Affairs partners.

Data Analysis & Documentation

• Analyze experimental and manufacturing data using statistical and scientific tools.
• Maintain accurate laboratory records and generate clear technical documentation.
• Contribute to regulatory filings (e.g. FDA – GRAS & DMF).
• Present results and recommendations to internal teams and leadership.

Skills and Experience

• Education:

• BS with 8+ yrs of industry experience in chemical engineering, chemistry, biochemistry, or related fields required.
• OR MS with 6+ yrs of industry experience
• OR PhD with 5+ yrs of industry experience

• Ability to effectively communicate and collaborate with interdisciplinary departments.

• Broad knowledge of process chemistry, biochemistry, bioprocessing, downstream processing, and/or chemical engineering.

• Proven track record working with development and manufacturing organizations (third-party preferred) to successfully perform technical transfers and deliver targeted commercial manufacturing processes.

• Experience developing regulated manufacturing processes (FDA regulation proficiency is considered a plus).

• Familiarity with natural products, enzymes, and/or nutraceuticals is considered a plus.

• Legal authorization to work in the United States on a full-time basis. Visa sponsorship for exceptional candidates may be considered.

Personal Attributes

• Entrepreneurial spirit and self-starter

• Team player and enjoys working with others, collaborative

• Excellent communication skills, written and verbal, including executive presentation

• A proactive, ambitious individual, willing to make the extra effort to achieve objectives and thrives in a stimulating, fast-paced environment

• Highest level of integrity, character and humility

A Diverse, Talent-Centered Culture Worth Joining

The challenges eXoZymes is working to solve — reimagining how ingredients and medicines are made through next-gen biomanufacturing — require the broadest possible range of perspectives, skills, and lived experiences. That’s why diversity isn’t a checkbox for us. It’s a scientific and strategic imperative.

Our team describes our culture as hardworking and innovative, deeply collaborative, and genuinely caring — and we mean all of it. We are a curious, ambitious, and international group of people who lead with trust, embrace new ideas, and support one another with kindness and humility. We believe that inclusive teams build better science, and we are committed to making eXoZymes a place where people of all backgrounds can do meaningful work, develop their skills, and build careers they’re proud of.

eXoZymes is an equal opportunity employer. All qualified applicants will be considered without regard to race, color, religion, creed, sex, sexual orientation, gender identity, marital status, national origin, age, veteran status, disability, or any other characteristic protected by law. Reasonable accommodations are available for qualified individuals with disabilities.

We welcome candidates from all backgrounds. If this role and this culture excite you, we want to hear from you. The future is bright — come help us build it.