Quick Info
Job Type
Full TimeSpecialty Skills
molecular biologydevelopmental biologychemistryclinical trainingtherapeutic programspreclinical developmentregulatory filingsINDCTNspayload validationdevelopment candidate selectionCMC timelinesbudget managementgo/no-go decisions0 1 medicinefirst-in-classnucleic acid medicinesmRNARNAiASOhepatic metabolismvascular biologyimmunologymulti-therapeutic area program leadershipUS regulatory filingsAUS/NZ regulatory filingsEU regulatory filingsMENA regulatory filings
About the Role
NewLimit is recruiting a Head of Translation to lead our therapeutic programs from discovery to the clinic. Our active programs are focused on restoring youthful hepatic metabolism, vascular endothelial integrity, and T cell immunity in aged and diseased patients.
In this role, you will lead the validation and preclinical development of reprogramming medicines through regulatory filing to early clinical development. You will serve as the company’s senior preclinical development scientist and as a member of our executive team.
As part of your role, you will:
- Lead preclinical development and preparing regulatory filings (IND, CTNs, and others) for reprogramming medicines. You will be the primary owner of progress for our therapeutic assets.
- Manage all Therapeutic Area teams and coordinate with others to establish preclinical models, validate payloads, and complete development candidate selections.
- Solve the logistical bottlenecks that block progress of our therapies. This may involve coordinating CMC timelines, planning study schedules, or sourcing precious preclinical samples. You will get your hands dirty.
- Serve as a member of NewLimit’s Executive Team and contribute to budgeting, goal setting, and technical review decisions.
- Recruit, manage, and mentor scientists and therapeutic developers throughout the company.