Director / Senior Director, Corporate Strategy & New Product Planning

Description

Headquarters Location: South San Francisco, CA, Company relocating to Emeryville, CA Fall of 2026

Candidate Location: Hybrid, Onsite 3 times per week

Travel Required: 5-10%

Reports To: Chief Business Officer, Senior Vice President, Business Development & Corporate Strategy

Department: Business Development & Corporate Strategy

Position Type: Full-time, Exempt

About CytomX Therapeutics:

CytomX Therapeutics, Inc. is committed to changing the treatment of cancer with our novel PROBODY® therapeutic platform. Our commitment to transforming lives with safer, more effective therapies is driven by our curiosity and passion for innovation and our belief that by acting with integrity in an honest, respectful, ethical manner, we have the power to change lives. Our workplace embodies collaboration, open communication, celebrating our successes, and holding each other to the highest possible standards. CytomX’s robust and differentiated pipeline comprises therapeutic candidates across multiple treatment modalities including antibody-drug conjugates (“ADCs”), T-cell engagers, and immune modulators such as cytokines. CytomX’s clinical-stage pipeline includes CX-2051 and CX-801. Learn more at www.cytomX.com.

Who You Are and What You’ll Do:

You are passionate about life sciences and making a difference to cancer patients, their families, and healthcare providers.CytomX Therapeutics is seeking a highly strategic and analytically rigorous leader to join the Corporate Strategy & Business Development organization as Director / Senior Director, Corporate Strategy & New Product Planning. Reporting to the SVP & Chief Business Officer, this individual will play a critical role in shaping portfolio strategy, informing pipeline investment decisions, and driving commercial and competitive insights across the Company’s oncology portfolio.

This position sits at the intersection of corporate strategy, pipeline planning, competitive intelligence, and new product commercialization. The successful candidate will partner cross-functionally with Research, Clinical Development, Commercial, Finance, Investor Relations, and Executive Leadership to help maximize the value of CytomX’s differentiated oncology pipeline and platform technologies.

The ideal candidate combines strong strategic thinking with operational execution, scientific curiosity, and deep understanding of oncology drug development and commercialization dynamics. This is a highly visible role requiring both strategic acumen and hands-on execution.

Job Responsibilities:

Corporate & Portfolio Strategy

• Support development and execution of CytomX’s corporate and portfolio strategy across wholly owned and partnered oncology programs.
• Lead strategic assessments of pipeline opportunities, indication prioritization, lifecycle expansion opportunities, and portfolio tradeoff decisions incorporating clinical, scientific, competitive, commercial, and financial considerations.
• Prepare commercial assessments and NPV models to support pipeline investment, portfolio prioritization, and business development decisions.
• Lead ad-hoc strategy projects commissioned by the CEO or CBO spanning R&D prioritization, resource allocation, financing strategy, and competitive positioning
• Prepare materials and strategic recommendations for Executive Leadership Team and Board discussions.

New Product Planning

• Lead commercial and strategic planning activities for early- and mid-stage oncology assets, including development of Target Product Profiles (TPPs), patient segmentation, differentiation strategy, and market opportunity assessments.
• Develop and maintain disease area landscape assessments, synthesizing epidemiology, market research, competitive intelligence, pricing and payer / patient access considerations into actionable insights that inform indication selection, clinical trial design, and regulatory strategy.
• Help maintain strategic forecasting and market models to support corporateplanning activities.
• Partner closely with Clinical Development and Translational teams to inform development strategy through the lens of future label, market positioning and unmet medical need.

Competitive Intelligence & Strategic Insights

• Monitor and synthesize competitive landscape developments across oncology, including ADCs and conditionally-active biologics.
• Develop strategic insights on emerging competitors, clinical data, partnering activity, and market dynamics.
• Generate actionable insights through primary and secondary market research, physician advisory boards, competitive intelligence, and market analytics.
• Assess evolving treatment paradigms, standard of care shifts, competitive readouts, and emerging technologies relevant to CytomX’s pipeline.

Cross-Functional Leadership

• Serve as a strategic thought partner across functions, helping align development strategy with commercial opportunity and corporate objectives.
• Collaborate with Business Development on diligence assessments, external opportunity evaluations, and strategic partnership discussions.
• Foster a collaborative, entrepreneurial, and data-driven culture aligned with CytomX’s mission and values.

Minimum Qualifications:

• Advanced degree required (MBA, PhD, PharmD, MD, or equivalent).
• Minimally 8 years of relevant experience for director level and 13 years of relevant experience for senior director level in biotech, biopharma, consulting, investment banking, or pharmaceutical strategy.
• Demonstrated success in corporate strategy, new product planning, portfolio strategy, commercial assessment, and/or business development.
• Strong commercial and financial acumen; proficiency in building and interpreting opportunity assessments, NPV models, and scenario analyses.
• Strong understanding of oncology clinical development, commercialization, and competitive dynamics; experience in antibody therapeutics, ADCs, immuno-oncology, or targeted therapies strongly preferred.
• Exceptional analytical and communication skills, including experience translating complex scientific and commercial information into clear strategic recommendations.
• Proven ability to influence cross-functional teams and operate effectively in a fast-paced, evolving biotech environment.

Preferred Qualifications:

• Strategic thinker with strong business judgment and intellectual curiosity.
• Comfortable navigating ambiguity and evolving priorities in a dynamic biotechnology environment.
• Collaborative, low-ego leader who thrives in cross-functional settings.
• Strong executive presence with ability to communicate effectively across technical and non-technical audiences.
• Detail-oriented while maintaining focus on broader corporate objectives.
• Passionate about advancing innovative therapies for patients with cancer.

How You Will Work:

• Demonstrates **collaboration and teamwork**. Works well with others and understands that collaboration leads to better results.
• Possesses strong **communication** skills. Communicates clearly, concisely, and professionally. Listens actively to build understanding.
• Exhibits strong **interpersonal** **skills** and **self-awareness**. Builds and cultivates strong and enduring relationships with others. Acts with humility and understands own strengths and weaknesses.
• Shows **continuous improvement** and a commitment to **self-management and development**. Operates with a continuous improvement mindset and continuously seeks to expand own knowledge and capabilities.
• Demonstrates a **patient focus**. Puts the patient first in actions and decisions taken.
• Contributes to **strategy** and **innovation**. Contributes to or leads elevating and actionable strategies. Ideates and creates unique opportunities to advance the organization.
• Demonstrates **leadership** and a commitment to organizational **values**. Takes ownership and has a strong sense of personal accountability. Consistently achieves or exceeds goals and expectations. Puts significant emphasis on living / upholding company values.
• Demonstrates ability and commitment to **building effective teams**. Attracts, develops, and retains diverse top talent. Aligns, mobilizes, and engages others to achieve and sustain peak performance.
• Has a track record of **driving vision and purpose** in teams.

Compensation, Benefits, and So Much More

• The expected salary range for this role based on the primary location for this position in the San Francisco Bay Area is $210,000.00 - $260,000.00 per year for director level and $245,000.00 - $295,000.00 per year for senior director level. Offer amounts are determined by factors such as experience, qualifications, geographic location, and other job-related factors permitted by law.
• A great environment where we work collaboratively, leverage each other’s strengths, and work toward a shared vision with our common goals of doing the best thing for patients.
• A robust and enduring approach to your development and career growth fueled by a strong learning curriculum and career guidance that helps you understand how you can grow your career at CytomX.
• A robust and highly competitive total rewards program that helps you achieve your compensation goals while supporting a great work / life balance.

Conditions of Employment

Background investigations are required for all positions at CytomX, consistent with applicable law.

CytomX’s Commitment to Diversity, Equity, Inclusion, and Belonging (DEIB)

CytomX believes that DEIB helps drive our success, and we encourage candidates from all identities, backgrounds, and abilities to apply. We are an equal opportunity employer committed to building an inclusive, innovative work environment with employees who reflect our values and ultimately, serve our patients. Therefore, in all aspects of the employment process, we provide employment opportunities to all qualified applicants without regard to race, color, religion, sex, disability, age, sexual orientation, gender identity or expression, pregnancy, medical condition related to pregnancy, creed, ancestry, national origin, marital status, genetic information, or military status, or any other protected status in accordance with applicable law.

Further, we are committed to the full inclusion of all qualified individuals. As part of this commitment, we (and the agencies we work with) will assist individuals who have a disability with any reasonable accommodation requests related to employment, including completing the application process, interviewing, completing any pre-employment testing, participating in the employee selection process, and/or to perform essential job functions where the requested accommodation does not impose an undue hardship. If you have a disability and require reasonable accommodation, or need other assistance in applying for or interviewing for this position, please direct your inquiries to Human Resources, at hr@cytomx.com

Notice to Recruiters/Staffing Agencies

Recruiters and staffing agencies should not contact CytomX Therapeutics through this page. We require that all Recruitment Vendors (e.g., search firms, recruitment agencies and staffing companies) have a fully executed, formal written agreement on file with CytomX prior to submitting candidates. Any resumes submitted through the website or directly by Recruitment Vendors will be considered unsolicited.Unsolicited vendor submissions do not constitute any actual or implied contract with CytomX, and CytomX will not be responsible for any purported fees. For more information, please contact our HR team at hr@cytomx.com

Please review our Applicant Personal Information Processing Notice to understand what types of personal information we collect from job applicants and why we process such information.