About This Role
We areseekinga highly motivated and creative Director of Chemistry to join our Small Molecule Chemical Development team. In this role, you will lead and mentor scientific and engineering teams as you guide project progression from early-phase through late-phase drug development. You will oversee the design and refinement of robust manufacturing processes for a wide range of small molecules, supporting pre-clinicaland clinical therapeutics. This role is integral to advancing our scientific endeavors, driving innovation, and enabling the successful launch of new medicines through collaborative, safe, economical, and sustainable process development.
Who We Are
We area team of organic chemistsand chemical engineersengaged in thedesignof innovativeprocesseswhichsupply new medicines to patients.Wefocus on developing safe, economical, sustainable,cost-effective,and robust processes to support clinical trials and the launch of new medicines across various drug modalities.We aredriven byfirstprinciplesscience, data-driven decision-making, and collaborative teamwork.
What You’ll Do
- Lead collaborativedevelopment and manufacturing teams to design and conduct experiments tooptimizeand characterize the processes ofBiogenassets with an emphasis on improvement in process understanding, robustness, and productivity.
- Design,guideand execute experimental plans to advance the Biogen portfolio. You willbe responsible forleading project teams towards the implementation of safe,efficientand robust chemicalprocessesBiogen drug candidates.You will collaborate with development and manufacturing teams tooptimizeand characterize the processes ofBiogenassets with an emphasis on improvement in process understanding, robustness, and productivity.
- Responsible for managing scientific colleagues, and mentoring, engaging, and preparingour future scientific and engineering leaders
- Develop the fundamentalprocessknowledge needed to support the transition of chemical and biochemical processes from laboratory scale to manufacturing partners.
- Collaborate with our Process Engineering, Analytical Chemistry, Oligo Synthesis, Solid Form, and Separations colleagues to develop the knowledge and controls needed for the supply of clinical materials and characterization of processes to support regulatory filings.
- Communicateproject teamresearch results effectively byinreports anddiscussionsin team meetings, including engagementin CMC activities including authoringCMCsection of INDs.
- Interact with Contract Research Organizations as project needs evolve, which may include travel
- Initiate innovative research projects to improve fundamental understanding and control of Biogen processes
- Expand on your Chemistry community presence professionallyrepresentingBiogen externally in consortia and conferences
Who You Are
You have a passion for exploring scientific concepts and are eager to contribute tothe design and development and execution ofcutting-edgetechnologiesin the service ofdelivering drug candidatesfor clinical trials. Your vision and dedication drive you to push the boundaries of scientific endeavors,ultimately impactingpatient lives. You thrive in a collaborative environmentwhere urgency,accountability,inclusionand integrity aresharedvalues.
- M.S. or PhDwith12+ years of relevant experience, including people management,in pharmaceutical or biotech settingsisrequired
- Strong background in the theory and practice ofpharmaceutical process chemistry and engineering, includingcommand of synthetic strategies, impurity controls, analytical, purification and isolation techniques, process characterization,familiarity with process safety and tech transfer protocols,and good problem-solving skillsin the service of delivering non-clinical and clinical APIs and the phase appropriate knowledge packages for CMC support.
- Demonstrated experience in leading project teams involved in delivery of APIs across several modalities
- Ability tolead teamsethically,collaboratively, effectively, and cross-functionally
- Excellentcommunicationand interpersonalskillsarerequiredalong withthedesire to work in ahighlycollaborative team environment.
Preferred Skills:
- Experience in engaging with external partners andrepresentingthe organization in external facing settings.
- Familiarity with regulatory requirements and CMC activities related to drug development.
