Director, Head of Predictive Modelling & Biopharmaceutics
Drug Discovery DevelopmentBachelor RequiredExecutive Director
Deep expertise in pharmaceutical development, predictive modelling and biopharmaceutics. Proven track record of successful application of mechanistic and PPBM modelling in drug development. Ability to work in a global ecosystem (internal and external) with a high degree of complexity and address the challenge with enterprise level perspective. Ability to lead/coordinate pipeline program and cross-functional initiative by mutually aligning different constraints and priorities with relevant stakeholder
Hires and mentors a group of predictive modelling scientists and engineers to execute Pharmaceutical Sciences in silico Modelling strategy for the oral drug product development department (ODPD). Influences direction through recognized expertise and strong cross-functional partnerships. Mobilizes and leads high-performing, cross-functional teams across multiple programs; driving alignment and disciplined execution. Champions change and inclusive leadership; develops the immediate team through coaching, mentoring, feedback, and deliberate skill building.
Operates with high autonomy and accountability to execute portfolio/program approaches, scientific plans, resourcing proposals, and partner models within agreed governance. Makes complex, risk-based decisions (or recommendations) on development approach, critical-path trade-offs, and mitigation actions across scope, budget, timeline, and quality; escalates appropriately and ensures decisions are documented and communicated. Anticipates program and capability needs and initiates actions to close gaps with minimal oversight.
Primary internal partners include other ODPD function heads and department members, other Pharmaceutical Sciences department stakeholders in AD and SMPD, Clinical Pharmacology and Drug metabolism (DMPK) Leads/Managers; Global Regulatory; quality; procurement/supplier management; and clinical biomarker development functions. Leads external technical interactions with consultants and development partners; supports contracting and governance interactions in partnership with legal and procurement.
Explores and evaluates emerging predictive modelling and biopharmaceutics technologies; proposes creative solutions to meet stakeholder needs and program constraints. Shares knowledge across the organization through technical reviews, best practices, and mentoring; encourages disciplined experimentation through prototyping and feasibility assessment.
Manages team across multiple interdependent workstreams spanning device development, patient testing services, and clinical research support across a global matrix. Navigates diverse external ecosystems (partners, suppliers, regulators) and varying regional regulatory pathways; balances speed, cost, quality and patient impact while operating under strict compliance and design control expectations.
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Boston, MA
$177,000.00 - $278,080.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
Takeda is an industry-leading, global pharmaceutical company with an unwavering dedication to putting patients at the center of everything we do. We live our values of Takeda-ism – Integrity, Fairness, Honesty, and Perseverance – and are united by our mission to strive towards Better Health and a Brighter Future for people worldwide through leading innovation in medicine. Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. At Takeda, you will make an impact on people’s lives – including your own. Takeda is an equal opportunity employer. For applicants of U.S and Puerto Rico positions: Click here to learn about our commitment to Equal Employment Opportunity (EEO). If you are limited in the ability to use our job application tool, or otherwise require a reasonable accommodation for a disability please click here. Read More