Clinical Trial Physician

About Us

At RayzeBio, every day is an opportunity to ignite meaningful change. As a wholly-owned subsidiary of Bristol Myers Squibb, RayzeBio blends the nimble, pioneering spirit of an emergent biotech with the global expertise and resources of a leading innovator in oncology. Our mission is to develop transformative radiopharmaceutical therapies that offer new hope for patients living with cancer. Here, you’ll join a multidisciplinary team where your ideas are valued, your expertise is amplified, and collaboration is at the heart of everything we do. From day one, expect to make an immediate impact—on our science, on our teams, and most importantly, on our patients. Learn more about RayzeBio: https://careers.bms.com/rayzebio/

The RayzeBio Clinical Trial Physician sits within Clinical Development, which is a global organization dedicated to the effective design and execution of radiopharmaceutical drug development. Clinical Development drives strategy, design, execution, and interpretation of clinical trials.

Position Summary / Objective

• Serves as a primary source of medical accountability and oversight for clinical trials
• Matrix management responsibilities across the internal and external network
• Manages Phase 1 – Phase 4 studies, with demonstrated decision making capabilities
• Provides medical and scientific expertise to cross-functional BMS colleagues

Responsibilities

Medical Monitoring

• Contributes to and is a key member of a high performing Study Execution Team
• Conducts medical data review of trial data, including eligibility review
• Holds responsibility for site interactions in partnership with the Clinical Scientist (CS) and Clinical Development Lead (CDL) for medical questions and education (including safety management guidelines in collaboration with Pharmacovigilance)
• Holds responsibility for assessment of key safety-related serious adverse events in partnership with Pharmacovigilance and oversees safety narratives, identification of safety signals and trends based on aggregate safety analyses
• Serve as 24-hour emergency medical contact (on rotational basis) and responsible for providing responses to medical queries from investigational sites, CRO teams and other study personnel
• Participate and contribute to study safety committee meetings such as Safety Review Committees (SRC), Data Review Committees (DRC) and/or Data Safety Monitoring Boards (DSMBs)
• Collaborates with CS/CDL and inputs into protocols, providing medical strategic oversight in protocol development (e.g. input on inclusion/exclusion, endpoints and assessments, dose modification guidelines and other safety-related clinical considerations), drafting/editing Medical Monitoring Plan (MMP) and Medical Data Review Plan (MDRP) documents.
• Liaise with CRO Medical Monitor (where applicable) to align on workflows, guidance to investigators, among others
• Fulfills GCP and compliance obligations for clinical conduct and maintains all required training
• Responsible for training internal and external team members in clinical protocol and related study-specific materials, product-specific training, including Investigator Meetings and Site Initiation Visits (SIVs)
• Provide medical input for Regulatory Authority responses, IRB/EC submissions, and Health Authority interactions
• Maintains regular communication with CDL and cross-functional team
• Identifies opportunities for streamlining MM workflows and works with appropriate parties to execute related initiatives

Clinical Development Expertise & Strategy

• In collaboration with the CDL, designs and develops clinical plans and protocols with a strong strategic focus based on knowledge of asset/drug, disease area and relevant science in order to meet regulatory and disease strategy targets
• Provides oversight and medical accountability for one or more studies
• Leads the analysis of benefit/risk for clinical development protocols in a matrix team environment working with CS
• Partners with CS/CDL to support executional delivery of studies (e.g., site activation, enrollment status, as well as adjudication for protocol violations, significant, non-significant deviations etc.)
• Identifies and builds relationships with principal investigators. Supports identification and cultivation of thought leaders to gain their inputs on emerging science in drug and biomarker research, disease knowledge, and design of clinical development studies and programs
• Maintains a strong medical/scientific reputation within the disease area. Has in-depth knowledge of etiology, natural history, diagnosis, and treatment of the disorder. Keeps up-to-date in the disease area by attending scientific conferences and ongoing review of the literature
• Keeps abreast of development and regulatory issues related to other competitive or relevant compounds in development and how our portfolio fits into the competitive landscape
• Provides ongoing medical education in partnership with CS/CDL to allow for protocol-specific training, supporting the study team, investigators, and others

Health Authority Interactions & Publications

• Contributes to key Health Authority interactions and advisory board meetings as Clinical Trial Physician
• Authors/drafts/edits clinical content for CSRs, regulatory reports, briefing books and submission documents to support closure, clinical narratives, reporting and filling of the study in partnership with CS/CDL

Degree Requirements

• MD required (or ex-US equivalent)

Experience Requirements

• 3 or more years of Industry experience and/or equivalent clinical trials experience is required

Key Competency Requirements

• Ability to communicate and present information clearly in scientific and clinical settings
• Board certification or eligibility in medical oncology or related field is desired
• Expertise in the scientific method to test hypotheses, including statistical design, analysis, and interpretation
• Knowledge of drug development process and ICH-GCP guidelines
• Knowledge of the components needed to execute an effective clinical plan and protocols
• Strong leadership skills with proven ability to lead and work effectively in a team environment
• Ability to leverage AI to drive program, portfolio, or functional performance through prioritization and scaled adoption

Travel Required

Domestic and International travel may be required up to 15%.

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Compensation Overview:

Princeton - NJ - US: $210,572 - $255,164 San Diego - CA - US: $227,418 - $275,577

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.

Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:

• Health Coverage: Medical, pharmacy, dental, and vision care.
• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.

Work-life benefits include:

Paid Time Off

• US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
• Phoenix, AZ, Puerto Rico and RayzeBio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays

Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

***Eligibility Disclosure:T_ he summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.

RayzeBio and Bristol Myers Squibb

RayzeBio was acquired by Bristol Myers Squibb (BMS) in 2024 and is a wholly-owned subsidiary of BMS; however, RayzeBio will continue to operate as a standalone organization.

Supporting People with Disabilities

BMS and RayzeBio are dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS and RayzeBio will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection/

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at TAEnablement@bms.com. Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response.